Friday, November 30, 2007

Profile: Paul Raj

Business India, January 24-February 4, 2001

Thinker, teacher, soldier, sailor: Paul Raj

Shivanand Kanavi

Rarely does one meet a personality with as varied an accomplishment list and as interesting a career path, as Prof A. Paul Raj, of Stanford University. When his name was suggested to us by another academic at IIT Madras, Ashok Jhunjhunwala, we dashed off an e-mail expressing our intent to meet him. We asked for an appointment, giving a brief outline of our purpose. We got a reply that said: "I am not sure whether I fit the profile of the people you are trying to meet. I worked for almost 25 years in the Indian Navy, now I am doing research and teaching at the EE department of Stanford University and have just done a startup called Gigabit Wireless (now renamed Iospan Wireless) while I was on sabbatical."

Our naval contacts said: "Oh Paul Raj, he was a most unusual whiz kid." Naturally, our antennae were up with curiosity to meet this off beat entrepreneur. When we met him, Paul Raj dropped names, accomplishments, career changes, patents and so on in his staccato narration of a fascinating story. It was so incredible, that we had to check with all sorts of sources to confirm various parts of the story, which we had heard sitting in a Palo Alto restaurant. Needless to say, it all checked out and we gladly admit our own ignorance in the subject.

Paul Raj joined the Indian Navy through the National Defence Academy and com­pleted his engineering degree from the Naval Engineering College at Lonavla. Since the degree was not recog­nised in those days by various non-military engineering colleges and IITS, it was not pos­sible for him to pursue higher studies. The naval brass, however, were impressed and, as a special case, sent Paul to IIT Delhi in 1969, for a MTech.

However, after the M-Tech, Prof P.V. Indire­san of IIT Delhi, encour­aged him to do a PhD. But the navy said no. Then, in the 1971 war with Pakistan, battle­ship INS Khukri was sunk, torpedoed by a Daphne class subma­rine at close quarters. Clearly, Khukri's sonar had failed to detect the attacking vessel. Khukri was sunk at around 1 am in the morning. At 6 am Paul was pulled out from IIT Delhi's campus and taken to Mumbai to see another ship of the same class and figure out how the Sonar failed. "I was very theoretical those days and even my thesis was in stochastic communication theory. But still I said that the sonar could be improved," says Paul. He worked on the problem at IIT Delhi and improved the sonar system by using techniques of digital signal process­ing. Bharat Dynamics manufactured it and put it into all Naval ships. It became a major success for Naval R&D.

"Then British Naval R&D invited me. There I discovered that India had given a majors Sonar contract to some British and French companies. I also found that we knew more about the system than they did. I told the navy that we would do it on our own. Between '77 and '82 we did a major project. Today, INS Delhi, INS Mysore and all other modern ships have my Sonar. In 1983, Indian Sonars were more advanced than American sonars and the CIA was very worried about whether we were selling them to the Russians. For shallow waters, it was the best in the world. It was unbelievable that we went from zero to there."

At that time, Paul got an offer from Prof Tom Kailath of Stanford University, a doyen in control systems, to teach in Stanford for two years. Paul finished the assignment, honed his research interests further and went back. "I was asked to start the Centre of Advanced Robotics and later the Centre for Development of Advanced Computing (CDAC). Meanwhile, I also built two labs for BEL. I started CDAC'S Bangalore centre to develop software. My view was: 'Let us not publicise too much.' I also felt that build­ing a parallel computer using transputers was an M-Tech project. What we needed was software for parallel process­ing without which we cannot use it, either for weather pre­diction or computational fluid dynamics. Because of these differences I left CDAC," says Paul.

Since he had already retired prematurely from the navy to join BEL, Paul was free to pursue his academic interests. In 1992, Paul joined Stanford as a faculty member. Here he switched to wireless. Today, his group at Stanford is recognised as a leader in wireless technologies in the world. It has done pio­neering work in space­time coding and modulation of wireless data.

"Our technology, in which I hold the princi­pal patent, is called MIMO (multiple input multiple out­put). It is a huge multiplier. It is like Wavelength Divisional Multiplexing (WDM). Just as WDM lets you shoot more data through different wavelengths, in MIMO every additional antenna gives you more bandwidth. We started Gigabit Wireless to develop broadband wireless access. Using our technology in fixed wireless, it will pro­vide 5-15 MBps bandwidth in a radius of five to ten miles. This will be way ahead of 3G," he adds. Iospan Wireless, formerly Gigabit Wireless, has 50 PhDs in a team of 150. Two major customers for Iospan are Worldcom and Sprint. The product is expected to ship in June 2000.

Paul Raj is a good friend of the Nambiars of BPL and is on their board. He is also trying to help the Navy by bring­ing in Naval students to Stanford. "The Navy is like a strong family, you can never forget them," says this part­sailor, part-teacher, part-thinker and part-tinkerer.
Clearly, Paul Raj is a man of many parts.

Friday, November 23, 2007

Profile: Vinod Khosla

Business India, January 24-February 4, 2001

Ceasar: Vinod Khosla

Shivanand Kanavi

You can put my name in any search engine and you will get enough mate­rial on me, and I have said whatever I have to say in most of my interviews. So you can dis­pense with the usual questions and fire away," said Vinod Khosla, when we met him in his office at Sand Hill Road at Menlo Park. The words were not tinged with arro­gance but were a genuine attempt at getting to the core issues quickly.

That is how Vinod has made his famous picks: Juniper Networks, Cerent, Sierra, Redback and more. Which, according to Fortune, have made over $16 billion for KPCB, thereby making him "the most successful vc of all times". Clearly he has gotten to the core of the next generation of networking.

Vinod is famous for his brevity. Rajvir Singh, who has become a fountain of Optical start-ups, recalls how the first thing Vinod advised him in an e-mail when he invested in Fiberlane (later split into Cerent and Sierra) was: "Keep the B.S. out of all communication".

We say amen to that, and give below a few notes from our conversation, albeit pared with Occam's razor:

Money: In 10 years I have never done a rate of return cal­culation. I have only looked at economic contribution. After all, if you have made economic contribution, then money will come anyway. Many people talk about how much they will be worth. I reject all those who only talk about money. That is Wall Street mentality. It goes against my intellectual curiosity, predicting trends and so on.

Venture Capitalism: It is all about helping entrepreneurs build companies. Juniper is a classic example. When Pradeep Sindhu came to me, he had no business experi­ence. I guided him in building Internet routers and then helped him find the team, I helped him find Scott Kriens. All these things are really hard to do if you are just an engi­neer, because you have never done anything like this. What we do is help make an idea into a company. It is like being a coach for a soccer team or a football team.

Startups: I do not miss being in a startup myself. It is a lot of work and you get stuck in one area. Technology is mov­ing rapidly in so many areas and I have interest in so many areas. Every two to three years I completely change the area I am investing in. I take a few months off to learn the whole technology and develop a vision of what the world is going to be like - it is literally going back to school- then start investing.

Current interests:
Whether it is optical components, which is physics and material science or enterprise soft­ware, the only way to do it is to take three months off, learn and come back. My position lets me do it. I have got curiosity. I change my interests regularly when I get bored .All three of my degrees are in com­pletely different areas. Right now, as hobbies, I keep up with string theory and evolutionary biology.

Big vs small companies: It is not big vs small. People who refused to take risks are losing. Lucent had more talent than Nortel. But Nor­tel has changed: they have absorbed entrepreneurial culture. Lucent has wrong acquisition strategy and wrong culture. People don't leave Cisco when it acquires, but they do when Lucent does. It is much harder for big companies but Nortel has done it.

Optical Networking: In both opti­cal and wireless, valuations are hyped and over-hyped. But if you look at the impact they are going to have on society, on the way business is going to be run and so on, then they are underestimated. Investors are like lemmings, suddenly they go from greed to fear.

Indian entrepreneurs: The stockmarket is not a good indicator. Some have built businesses but some have built market caps. It is a bad value system. Issue is what can you create that has lasting value. Desh has real rev­enue. I like what Desh did. In the end his value will be judged if he makes an eco­nomic contribution. That is what Pradeep is doing. Intel, Sun, Dell, Microsft, Oracle all made contributions.

Education in India: A country of the size of India, a billion strong, does not have a major university which is world class and which is leading in research so that it does not have to depend on all the research in US. You have to take a SO-year view of this, not five to ten years. Over the long haul, India has the talent, language (English), enough infrastructure. It will grow in a very, very big way in the knowledge economy. Hopefully, people from all over the world will go to India to do research. That is the genesis of my interest in Global Institutes of Science and Technology.

Role models: I was 15-16 and living in Dehi Cantonment, as my father was in the army. I used to go to Shankar market and rent old issues of trade journals in electronics, which you get free there. I read about Intel being started up by a couple of engineers. That was my dream long before I went to lIT. In 1975, even before I finished lIT, I tried to start a company. Those days in India, it was not possible if your father did not have connections. That is why I resonate with role models. Andy Grove and Intel became role models for me.

Vinod Khosla loves travel and photography. Blown up pictures of his children taken by him are all over his office

Weather forecasting, Monsoon

The Weekend Observer, June 1992

Vagaries of weather forecasting

Shivanand Kanavi

The monsoon is not only a meteorological phenomenon for Indians but it deeply affects their literature, music, culture and the very psyche itself. Not only are the famous raga Megh Malhar and the poetic work Meghdoot expressions of it, but D.D. Kosambi, one of the great Indian encyclopaedists observed that the regularity of the cycle of seasons might have given rise to a fatalistic world view and even the myth of satyug, tretayug, dwaparyug and kalyug

Thus anybody who can predict and hopefully change the pattern of monsoons is always sought after, be they sooth sayers, astrologers, sadhus, performing yajnas and havans and even scientists. When the predictions or promised changes in weather do not come through, Indians seem to find any number of justifications for the failure of all the traditional wisdom but the meteorologist is never spared. He is the cartoonist’s delight. Who can forget R.K. Laxman’s cartoon of a long bus queue in pouring rain where everybody has provided himself with a raincoat or an umbrella except one fellow, and a guy whispering “must be from the weather bureau”!

All this is good for a laugh but when you meet a hardened weatherman like Dr. S Kumar, Deputy Director General of Meteorology heading the Colaba (Bombay) observatory and responsible for the western zone, and learn the rudiments of meteorology then you start appreciating the complexity of the subject.

The word monsoon owes its origin to the Arabic word mausam meaning season. It is believed to have been used by seamen, six or seven centuries ago to describe a system of alternating winds in the Arabian sea, these winds appear to blow from northeast for six months and from the southwest for another six months. Seasonal changes of wind are primarily the result of differences in the quantity of heat received from the sun by different parts of the earth.

As a consequence of its chemical composition and its soil structure, the conduction of heat into the earth is a comparatively slow process. Thus most of the solar energy received at the ground by the continents is used up in hating air rather than the earth’s surface. Whereas oceans are heated up to greater depths due to convection currents and a smaller part of the energy is available for heating the air, monsoon as a system of winds has the following notable features:
1. A system, with marked seasonal shifts, caused by the differential heating of the land and the sea.
2. A wind system that is largely confined to the tropics, that is the region between 20° N and 20° S latitudes on both sides of the equator.
3. Indian monsoon can be thought of as southeast trade winds which on crossing the equator are deflected to the right by the earth’s rotation (Coriolis force) and hence approach the land from a south-westerly direction.
4. The trade winds of the northern and southern hemispheres are divided by the Inter Tropical Front (ITF) which is a region of considerable cloudiness and rainfall. The southwest monsoon, originates in the ITF and moves northwards, due to the pull of a low pressure area in the hot Indo-Gangetic basin, but of the subcontinent after reaching the southern tip of India around June 1, it splits into two branches; the Arabian sea branch, and the Bay of Bengal branch.

The Arabian Sea branch gradually advances northwards to Bombay. The advance from Trivandrum to Bombay takes about ten days and is fairly rapid.

The Bay of Bengal branch moves northwards into the central Bay of Bengal and rapidly spreads over most of Assam by the first week of June. On reaching the Himalayan barrier, the bay branch of the monsoon is deflected westwards. As a consequence, its further progress is towards the Gangetic plains of India rather than towards Burma. The arrival of monsoon at Calcutta is lightly earlier than at Bombay. By mid-June, the Arabian Sea branch spreads over Saurashtra-Kutch and the central parts of the country. Thereafter the two branches tend to merge into a single current. The remaining parts of western UP, Haryana, Punjab and the eastern Rajasthan experience the first monsoon showers by the first of July. Some times the first showers at Delhi arrive from the east as an extension of the Bay of Bengal branch and sometimes from the south that is from the Arabian sea branch. Often it is a race between the two. By mid July it will extend to Kashmir and remaining parts of the country but only as a feeble current because by this time it has shed most of its moisture.

The normal duration of monsoon varies from two to four months. The withdrawal is much more gradual than its onset. Generally the monsoon withdraws from northwest India by the beginning of October and from the remaining parts of the country by the end of November. Though theoretically it seems possible for both the southwest monsoon and the northeast monsoons to co-exist in the southern half of the peninsula in October, in reality such situations are rare.

This in brief is the story of the monsoon but there are any number of disturbances of local and regional origin that can upset the text book schedule for example a cyclone in the Arabian sea that starts drawing the moisture away can lead to delays and dissipations.

The short term forecasts deal with a period of twenty four to seventy two hours which are mainly done with the help of data from over 500 weather stations spread all over the country, the data from the ships in the ocean, the satellite pictures from he NASA polar satellite NOVA which scans India every six hours, pictures from the geo-stationary INSAT satellite and even input from airline crews.

But a satellite picture, as Dr Kumar points out, is like a X-Ray photograph in the hands of a physician. It needs interpretation which is bound to be subjective. This is where the years of experience of our weathermen count.

Attempts are on to developing computer programmes to forecast weather in the medium term that is three to ten days at the Super Computer facility in Delhi.

The long term forecasting that is from ten days to a few months, is being attempted by the group in Pune. Over sixteen phenomenons all over the globe are being watched by this group and correlated with the Indian monsoon. Some of tem are the total snowfall over Eurasia during the previous winter, the convective wind between Darwin in the southern hemisphere and Tahiti islands in the pacific, the El Nino oceanic current off the coast of Peru in south America etc.

Considering the enormity of a weather system like the Indian monsoon, and the usual constraints of funds and technology and the very nature of a field where controlled experiments are well nigh impossible, our weathermen are doing a competent job, to say the least.

Tuesday, November 13, 2007

Optical Networking, Tejas

Business India, August 7-20, 2000

Will Tejas light up?

Brought into being by Sycamore Networks, ASG-Omni and Desh Deshpande, the new technology baby in Bangalore, Tejas Network, aims to put India on the global hi-tech map

Shivanand Kanavi

“The bible of Optical Networking, which we all study at Sycamore and other Optical Networking companies, was written by this guy, in Bangalore," said Gururaj 'Desh' Deshpande introducing Dr Kumar Sivarajan, chief technology officer of Tejas Networks, while launching Tejas recently. "The technology business is totally people centric. If you have a world-class team, then you can compete in the global market. Our first milestone is recruiting 100 world class people with the right mindset in the next six-nine months," adds Sanjay Nayak, CEO, Tejas Networks.

"Tejas will be India's first globally competitive product company," says Deshpande. With that kind of confidence bordering on cockiness, Tejas was launched in a simple function in Bangalore on 25 July. Tejas aims to develop products for the fast growing optical networking market, which is expected to reach $40 billion by 2004 and also sell and support Sycamore's optical networking products.

Everybody in India claims to be globally competitive, "state-of-the-art,” etc which needs to be taken, not with just a pinch of salt, but a fistful. However what makes Tejas special is the track record of the team which is launching it. Deshpande, founder and chairman of Tejas, is fast becoming a folk hero in India. Though Deshpande has been a successful entrepreneur in North America for almost 20 years, what made him an icon in India, and a highly-respected figure in the cutthroat US market itself, is the launch of his third startup Sycamore in 1998. The Sycamore share which was offered during late 1999 on Nasdaq at $38 listed at $210. A start-up struck a market cap of about $18 billion within weeks of listing and is currently valued around $35 billion, of which Deshpande owns 29 per cent.

"The new economy unfairly rewards excellence and unfairly punishes mediocrity," says Deshpande. "Today markets do not look at your balance sheets and revenue streams to decide on valuations. They are looking at the people leading the company, their track record in trying their darnest to turn their convictions into reality. There is no stigma attached to failure as long as you did your best in a transparent way. After all, one of my start ups, Coral Networks did not work out and when I disagreed with my partner on business strategy, I had to walk out. At that time, my wife had also given up her job to bring up our children and we had to manage our family with no income for 9-10 months. But I still decided to quit Coral and start a new company called Cascade Communications which took a longtime to attract any investment by venture capitalists," adds he. Later, of course, Cascade grew into a large company with $500 million in revenues prior to its acquisition by Ascend Communications in June 1997 for $3.7 billion. (Ascend in turn was acquired by Lucent.)
.
"Sanjay has been a successful CEO when he headed Synopsys India, and View Logic's operations in India. Similarly Kumar Sivarajan who was working in the Indian Institute of Science, Bangalore has earlier worked in Caltech and IBM'S Watson Research Centre. Our director engineering Arnob Roy has over 13 years of industry experience and has contributed significantly to product development in Synopsys, View Logic Systems and Cadence Design Systems and is an expert in Electronic Design Automation. We have in a short period of time recruited about 17 excellent people and are already talking to our first customers," says Deshpande.


"Products company is a big poker game,” Desh Deshpande

Q. Why is Tejas the first such start-up in India?
A. Products is a very different game. It requires a different level of confidence. In the services business you boot strap. You put some money in, more comes out. You use it to expand etc. It is a cost plus business. The product business is a big gamble. You have to say: here is my 25 million dollars, bang. It is a big poker game. That is not the culture that exists in India. It exists only in US, nowhere else in the world. That is the culture I built my business on. That is the only thing that I know how to do. I don't know how to build a service business.

Q. Will Tejas support Sycamore products worldwide?
A. Absolutely. You build the capabilities and then go wherever you can. So the professional services group in Tejas will go to the US, China, Malaysia, Indonesia and so on. There won't be any territorial issues. Right now the market is growing at such a rapid pace that everybody can have a piece of the pie if they can deliver.

Q. You promise bandwidth nirvana, but do you have a problem of bandwidth in India for Tejas? A. Of course. The amount of money you have to pay in India is ridiculous. For a 2 MB pipe to US, it is $50,000 a month. In Europe, it is $3,500 a year and Singapore it is even cheaper.

Q. Europe is a large market, so if closeness to market is the issue then how come there are no great product companies from Europe except in mobile telephony?
A. Because they are not entrepreneurial. It's the same thing in Japan. You look at Siemens, Alcatel, etc, they are not entrepreneurial. They cannot think out of the box, they cannot innovate. As a result, all these companies and countries are very good at going after a large market: 1 million cars, 100 million watches, 10 million cameras, they are good at that. But whenever the market changes very rapidly where you have to innovate and competition is very intense, they are not good at it. The only country which has done very well in such markets is the US, because they are a very, very open country. They do not say, "Hey Desh, you are from India and so you cannot set up a company in the US. So you can get the best people in the world and go after the competition. India needs to do the same thing.
Indians are very entrepreneurial too; that is why they have done very well in the US. You need people in India with ambition, you need role models and benchmarks. After all, one lives against so many odds here that you have to be entrepreneurial. There are a few start-ups in Bangalore but you need a big hit.

Q. There is a lot at stake in Tejas since everybody will be watching it. Does that create pressure?
A. No. If you want to win the Olympics then you have to say I am going to win it and you will be watched every minute of your life and you have to live up to it. But you have to sign up. If you don't, you will never win

Q. DoT has about 200, 000 km of fibre in the ground. What if it teams up with you and provide all the bandwidth we need.
A. Internationally innovation does not favour the incumbent. Look at AT&T, Mel, WorldComm, Sprint and so on. If they all did the right things, there would never be a Williams, Quest, Level Three and any of these guys. It is the speed at which you can implement and innovate which creates a brand new market. If you open up the market, there is always room for others. DoT's market share which is 1 00 per cent now will fall, but its revenues will go up. There is not enough fibre in India which will meet the demand for next 1 0 years, so there have to be a lot of players.
Today in the US, voice is practically free. It used to be 50 cents a minute and now it is 1 .5 cents. It (demand) will come from data and new applications which require high bandwidth. Pure capacity is also not an issue, it is speed of service, quality of service, etc. For example you go to a company and say I need 2 GB for two days from Mumbai to Delhi and one guy says I have got 1 00 GB capacity but it will take me six months to give it to you and then you have to sign up for five years and another guy says it will take me five minutes and I will give it to you for two days, then the second guy wins.



"The speed with which this project has been taken from concept to market place is truly amazing and is setting new benchmarks," says Ashok Vasudevan of ASG-omni, a Connecticut-based consulting and incubating firm. "In less than three months we incorporated it, recruited our top team and got our office ready from scratch to where a hundred people can work. Even in Boston this is difficult to beat," adds he.

"In fact Sanjay Nayak, our CEO, joined in two-and-a-half days," says Hans Taparia another member of the ASG-omni team who is involved with Tejas. "We had breakfast one day, he took the evening flight to Boston, spent a day with Desh and Sycamore, he returned the next and joined us as CEO!"

"The way Sanjay was talking to other people while interviewing for Tejas was like a veteran of many years. It is conviction that matters. Once you have people who have the conviction then you need the structure that gives them the independence. Kumar and Sanjay have the full power to take whatever decisions and we are there just to help. If this was a startup of a couple of people in Bangalore then you would not have the confidence, but if you know that you are going after a $40 billion market in 2004 and you have the right group of people then you will invest a lot of money. The confidence comes because Tejas is associated with Sycamore, that means you have market access," emphasises Deshpande.

How much money have the three promoters Deshpande, Sycamore and ASG-Omni put into Tejas? They are still very tightlipped about it. "We will disclose it at the right time but money is not a problem. At Sycamore itself we are sitting on $1.5 billion in cash after our IPQ, which is more than many of our large competitors. But I am on the board, Kevin Oye of Sycamore is on the board. Our management time is at a premium and I am spending a lot of time here. We are looking for some thing really big here," says Deshpande.

We have had several very successful software services startups in India which have become world class services companies. However, we still do not have a successful technology products company. One reason that has been always given by the industry pundits is that we are far from the market place (read the US). So will Sycamore playa facilitating role in this startup? "Definitely. Access to market knowledge is an absolute must for any product company, but Sycamore will straightaway provide a tunnel into the US market, which is still the most important market. Tejas is at a different vantage point from Sycamore. Sycamore had to live on its own, it had to compete with Lucent, Nortel and all the big boys. Tejas does not have to fight for survival, it just has to execute. If you can get 100 very, very talented people with a certain culture then that is a huge asset. To build products you need market knowledge, you need the process, domain knowledge, etc of world class which does not exist in Bangalore. So you need a lot of interaction with Sycamore and that is what we have been doing. Some of the speed at Tejas is coming from there. At Sycamore we take a lot of pride in all this. Everybody says the last guy did something in 30 days and I will do it in 27 days and so on. You can already see the flavour of that at Tejas and once you have the culture and the machinery to execute, then developing products is just identifying the right target and going after it," explains Deshpande.

"If it needs about $25 million to develop a world class product, it does not mean that anybody with $25 million can successfully build a product. It needs deep market knowledge and domain knowledge. Thus Sycamore is key to Tejas' success," adds he.

Tejas will have two divisions working in tandem. One at product development and the other vending Sycamore products in India which will also build capabilities for network design, deployment and support. The Tejas team is already talking to many people in India who have declared their intention to build large, broadband networks.

So what is new? Have not all Indian companies started with services and then slowly ventured into components and products? The crucial thing is not to look at services as bread and butter and invest the revenues from services into product development later, as is wont with Indian companies. The services team will build for the global market. "Even this is being done with our product strategy in mind; after all there is a lot more to do in a product company than just build products. While we build a world class R&D centre for products we will be building a sales and marketing network for Sycamore's products which will be very crucial when we come out with our own products. Opportunities will not wait at that time for us to build up our marketing," adds Sanjay Nayak.

"People like Sanjay and Kumar would not have joined us if we had started a sales office for Sycamore. Such talent can be attracted only if it is a product startup with all the attendant challenges and rewards. They have built products in the past, but for others. Now they will be doing it for themselves," says Deshpande.

Tejas, is a Sanskrit word that means brilliance, radiance and energy. A million eyes are literally watching Tejas to see if it will light up. For their first product roll out, watch this space.

Brahmi, Memory enhancing pills

Will you remember to take your memory pills? 
(This article was written for the 'dummy' edition of India's first Personal Finance Magazine in Jan 1998)

Middle- aged people with failing memories, parents pushing their children to join IITs, students cramming the year’s syllabus a month before exams- these are being targeted by the manufacturers of memory-enhancing drugs. Shivanand Kanavi investigates the efficacy of these drugs. 
“I trust Memory Plus,” grandmaster Vishwanathan Anand has been assuring TV audiences in the country. Though he does not explicitly say that regular ingestion of Memory Plus helped him achieve phenomenal success in world chess, that is what the ad implies. 
 Velvette International Pharma Products Ltd., a Madras-based listed company, introduced the product in the market in July 1996. Whether the drug really had an effect on Anand during the past 18 months is a moot point. Anand was a grandmaster well before the drug was launched. 
 According to V.P. Kambhoj, an eminent drug researcher and scientist emeritus at the Central Drug Research Institute, Lucknow, Memory Plus has been tested on mice for several years, It does improve the “Short-term and long-term memory” of mice. 
 But, hey, we want to know if we can become grandmasters after a course of Memory Plus! Conclusive proof of Memory Plus helping human beings has yet to come. Kambhoj says data is being collected at various research centres about its effectiveness on human beings. One thing is certain, says Kambhoj: the drug is not toxic. 
In accordance with the standards of modern medicine, research at the CDRI has shown that Memory Plus does not have any harmful side-effects on human beings. According to C.K. Rajkumar, Velvette International’s effervescent managing director, trials on the drug’s effect on the elderly are now under way at the Ayurvedic Research Centre at G.S. Medical College, attached to the well-known King Edward Memorial (KEM) Hospital in Mumbai. 
 In short, it is still an open question whether your memory will improve if you do remember to take your two tablets of Memory Plus a day for 90 days (a box of 30 pills costs Rs.105). You can’t be sure whether your investment of over Rs.630 on these tablets has improved your memory. By the time you finish the course, however, there is one thing you are unlikely to forget: how much you spent on it. 
 Research conducted on mice at the Industrial Toxicology Research Centre at Lucknow has shown that Memory Plus reduces anxiety and stress. Researchers found that Memory plus lowered the levels of HSP-70, a protein associated with stress, in the brain cells of mice. The active ingredients in Memory Plus, which were chemically isolated by the CDRI, are called triterpenoid glycosides. They are also known as bacosides A and B, as they are extracted from the Brahmi plant (bacopa munniera). 
 In the Charak Samhita, written nearly 2,000 years ago, Brahmi has been prescribed as a nerve tonic for “anxiety, weak intellect and lack of concentration”. The Sushruta Samhita, written about 100 years later, also mentions Brahmi as “effective for loss of memory and intellect”. Still later Ayurveda texts also sang hosannas to the powers of Brahmi. Brahmi extracts have been indicated as therapeutic for patients of epilepsy and asthma as well. This is why the CDRI took up the study of Brahmi in the 1960s, using modern pharmacological and chemical means. 
 Today, Memory Plus is being marketed as a herbal medicine and not as an allopathic drug. The studies conducted so far are more than enough to qualify it for such a label. Since 1976, the World Health Organisation has allowed the introduction of traditional medicines into the market without further clinical trials, provided they have been in use for a long time. Brahmi, which has been used in India for thousands of years, certainly qualifies. 
 Rajkumar seized upon the idea, bought from the CDRI the technology for separating enough bacosides in the very first extract of Brahmi, and introduced Memory Plus. He has pulled off a coup of sorts in imaginative marketing. Within the first 15 months, he claims, he sold about Rs.15crore of Memory Plus, making other pharma entrepreneurs jealous. International enquiries are pouring in, and Velvette Pharma recently launched the drug in Sri Lnaka and Malaysia. 
 FLATTERY BY IMITATION 
 The ultimate tribute to success is imitation. Dalmia Industries Ltd., the New Delhi-based Sanjay Dalmia group Company, has introduced a drug called MegaMind  Plus(available for Rs 108). It contains a Brahmi extract, and small amounts of a herb called vacha. The company introduced it in July 1997, and says it is too early to provided sales data. It explains that, while Brahmi is recommended for retention of facts, vacha helps recall. 
Whether human memory can be divided into retention and recall is a big question. But the company claims that G P Dube of the Centre of Psychosomatic and Biofeedback Medicine at the Banaras Hindu University has researched the drug’s efficacy on human beings. Dube claims that trials on normal people, as well as on those with degenerating memories, showed beneficial effects. Ayurveda, and not modern medicine, motivated his work. However, Dube has not been able to chemically isolate the active compounds. 
 Dalmia Industries is banking on Dube's preliminary tests and advertising the drug as having been tested on human beings- a questionable claim indeed. Without getting into the controversy of “retention and recall”, Dube claims that the use of small amounts of vacha, an ingredient of MegaMind, helps people with communication difficulties like stuttering and stammering. 
 So, for now, we have to depend on testimony of our grandmaster, roped in by Memory Plus, or some other celebrity that the makers of MegaMind may rope in tomorrow. 
If you do want to give in a try, remember to take the drug regularly without skipping a day. Both manufacturers warn that if you miss even one dose, the drug may not be effective. 
But if you can remember to take your two tablets every single day for three whole months, then do you really need the drug?

Tuesday, October 23, 2007

Auto emission norms India

Business India, May 31-June 13, 1999

Clearing up emissions

Thanks to the Supreme Court, Indian consumers will see a major leap in automotive technology and fuel quality

Shivanand Kanavi

By the stroke of a pen, the Supreme Court pushed the Indian auto industry into a technological leap. Since then, the media has been filled with smog about Euro-I and Euro-II for almost two weeks. But what are these norms and more importantly what are the factors responsible for the high levels of auto emissions and what are the technologies available for mitigating them? Which of these technologies are likely to be brought into India to meet the new norms? These are some of the questions that Business India looked into.

Not that the technologies involved in abating auto-emissions are of the cutting edge variety, but Indian consumers have been denied them for two reasons. First of all, they need further investments in automotive engines, catalytic converters, and oil refineries and secondly they would push up the price of an automobile by about 10 per cent in a highly price sensitive market.

But the increasing awareness about the health hazards posed by constituents of auto exhaust like smoke (particulate matter), nitrogen oxides (NOX), carbon monoxide (CO), benzene, unburnt fuel (HC), lead and so on, especially in highly congested Indian cities, has been steadily forcing the government and the auto industry to gear up to cut the emissions. Accordingly, the government brought in unleaded petrol in 1996 in the metro cities and brought in new emission norms into force the same year.

The ministry of surface transport moved to notify India 2000 norms in August 1997. These norms were derived from the Euro-I norms (see table). They required lower sulphur levels and the refineries were advised to invest in hydro-desulphurisation to reduce sulphur content in diesel to 0.25 per cent.

It is important to understand that the emissions from an engine depend on how the engine is driven. How frequently do you brake? How frequently do you shift gears? What are your cruising speeds? What is your top speed? Do you check the emissions after the engine is warmed up or from a cold start? What about emissions due to evaporation of fuel from the automobile? And so on and so forth. A detailed study of the actual driving conditions: road conditions, traffic conditions, rush hour, off rush hour etc. has to be made. Then one arrives at what auto engineers call, the driving cycle. Then there are two ways of testing the vehicles: the engine dynamometer test and the chassis dynamometer test.

Thus Euro norms are not just some figures for various constituents of exhaust but also they per force specify the European Driving Cycle. Thus our table is a highly simplified version of the norms and does not cover two-three wheelers. Developing the driving cycle is a long drawn out affair and the data needs to be continuously updated as traffic conditions and road conditions change. So, for pragmatic reasons, the European Driving Cycle has been adopted with some modifications, like the top speed of 120 kmph has been reduced to 90 kmph.

The industry was gearing up to meet the Euro-I norms by 1 April 2000 in terms of vendor development, engine improvement, etc, and so were the refiners gearing up to improve fuel quality. There was also discussion going on about further cutting down emissions by 2005, which would be more in consonance with the Euro-II norms. However the increasing pollution in Delhi, (though polluting vehicles are not the only culprits) led the Supreme Court to bring forward the deadline for India-2000 norms to 1 June 1999, instead of 1 April 2000, as far as Delhi is concerned. The government was also directed to notify the equivalent of Euro-II norms with utmost speed and bring them into effect from 1 April 2000 - a five-year leap. The move naturally sent the automobile manufacturers into a tizzy. Though the order pertains to the National Capital Region around Delhi - which has the dubious distinction of being the fourth most polluted city in the world - it is clear that this might soon be extended all over India.

Despite a battery of the best and brightest lawyers arguing for extension of the deadlines on behalf of the auto manufacturers the court stuck to its guns. Now, work has to be taken up on a war footing on several fronts to achieve
these laudable objectives. First of all, the government has to quickly notify the Euro-II norms (for want of a better term). The Automobile Research Association of India (ARAI), an industry funded organisation that is affiliated to the industry ministry, has to gear itself up for quick certification of various models that are going to pour into its labs. S.R. Puranik, director of the lab, says the institute has already certified nearly seven petrol driven models and 11 diesel driven models for India 2000. He pointed out that once the Euro-I1 norms are notified ARAI can do the emission tests in two-three days per model and the detailed certification under Central Motor Vehicle Regulation which requires noise and safety tests along with emission tests in two-three weeks per model.

Another important issue is the quality of fuel required to meet the Euro-II norms. The question of fuel quality has to be addressed very seriously since the new norms will require not 0.25 per cent of sulphur but 0.05 per cent. So far only Reliance has said that it will be able to supply such fuel from July 1999, when its giant 27 million-tonne refinery goes on stream. Others are still working out the consequences of these norms. A.K. Jain and K.K. Gandhi, scientists at the Indian Institute of Petroleum, Dehradun, point out that the fuel required to satisfy lower emission norms has to satisfy several criteria. For example, the sulphur content of petrol has to be brought down as well. Moreover, benzene and aromatic content has to brought down, volatility of the fuel has to be controlled carefully as it influences' the warm up time and evaporative emissions, oxygenated blend components to reduce co and HC emissions have to be added, multifunctional additives to control deposit formation within the engine have to be added and so on. Similarly, according to Jain and Gandhi, the diesel required has to not only have 0.05 per cent sulphur but also a lower density, lower boiling point (from 370 celsius to 340 celsius) higher cetane number (from 45 to 49-53 low aromatics, good oxidation stability and lesser amount of heavy cuts blended.

While the refiners upgrade themselves to meet these requirements, auto component manufacturers and auto makers have a lot of work to do. Automobile engines, be they petrol fuelled or diesel fuelled, are powered by burning fuel inside the engine in an explosive fashion. In a petrol engine, a mixture of petrol and air is compressed and is ignited by a spark from the spark plug. The combustion, however, takes place best when the air to fuel ratio is 14.7. However, even the most sophisticated carburettors rarely achieve this ratio and definitely not under all driving conditions. A multi point fuel injection (MPFI) system, which is controlled by a micro chip called electronic control unit (ECU) can achieve much less emissions and better fuel efficiency in petrol engines. Better combustion lowers HC and co emissions but can lead to higher NOX emissions. Improved catalytic converters like pre-heated or dose loop ones can take care of most of the noxious matter.

In the case of diesel engines, turbo charging inter-cooling, exhaust gas re-circulation, de-Nox catalytic converters, higher injection pressures, particulate traps and so on can similarly ensure that Euro-II norms are met. The technologies likely to be brought into India at the moment are multi point fuel injection with electronic control unit (not the state of the art engine management system), better catalytic converters, higher injection pressures for diesel engines and at least' soft' turbo charging - that is turbo charging to cut emissions but not for increasing the power since that will require major changes in the drive train. It is estimated that the new technologies can cost up to 10 per cent of the present vehicle price.

These are all proven technologies; though none of them are cutting edge the issue is: can changes in mass production be made within the stipulated time at the lowest cost to consumers? The coming months will prove as to who among the various vehicle makers is up to the task.

Process Engineering, de-bottlencking, Chemical Industry

Business India, December 28-January 10, 1999
More from less

Debottlenecking has become a mantra to help chemical companies stay a float during hard times

Shivanand Kanavi

For years, M.M. Sharma, FRS, the doyen of Indian chemical engineers, used tacky slogans in every chemical industry meet to propagate the importance of clever R&D for healthy bottom lines. "More from less!", "Convert liabilities into assets!", "Knowledge engineering!" were some of them. The response was mixed. Protected markets and lack of serious domestic competition due to licensing were hardly the ideal conditions to breed lean and mean companies. However, the current hard times have more than convinced many businessmen of the wisdom of these words. In smart companies, these slogans have led the effort in intensive debottleneckrng, leading to tangible benefits. The list of 'smart' companies is long. It includes giants like Reliance, IPCL, the psu oil refineries engaged in commodity chemical business as well as midsize players like Arti Organics, Herdillia Chemicals, Excel, Bombay Oil, Hindustan Organic Chemicals, Atul and Alkyl Amines who have a mixed portfolio of commodity and specialty chemicals or purely specialty chemical players in the pharmaceutical industry like Ranbaxy.

It is not that the tongue twister, "debottlenecking" is new to the chemical industry. In fact, under the licence raj many companies used to report that they debottlenecked and increased the capacity at an incremental cost, as soon as the government increased their licensed capacity. This made their claims largely suspect. It was assumed that the declared capacity was understated in the first place. With liberalisation, there is no incentive to understate capacity. Now, chemical imports are pushing the price level down, export markets are under great pressure, most greenfield projects are being shelved, profit margins are thin and any incremental innovation is welcomed. Thus, debottlenecking is turning into a fine art.

The word "debottlenecking", though it does not occur in any dictionary, means removing the bottlenecks in a process. The exercise consists of identifying the bottlenecks and then removing them one by one. There are many levels at which the process works. The more pedestrian level is of making a physical analysis of the equipment in the plant like pumps, compressors and distillation columns. This can lead to clues to increasing the capacity of particular compressors, pumps, etc, leading to higher throughput. This can be called level one debottlenecking. Due to overdesign by plant designers (as they have to give guaranteed performance in terms of throughput, quality, etc) there is always scope to increase the plant rough put by 25 per cent with hardly ny additional investment. A more thor ugh analysis and some marginal investment can readily yield 50-60 per cent increase. For example, Reliance is currently manufacturing about 250,000 tonnes of PT A from a 180,000-tpa plant at Patalganga near Mumbai. There are reasons to believe that soon it may go up to even 300,000 tonnes. The lessons learnt here are being readily applied in the larger plants at Hazira, where two 350,000-tonne PTA plants are being fine-tuned to yield 500,000 tonnes each. Some RIL engineers believe that this can be further increased to 600,000 tonnes each. In fact, ICI plants in Wilton, UK were debottlenecked after learning from the experience at Reliance.

The second level consists of improving the design of equipment like columns, heat exchangers and reactors. -Por example, using appropriate packing in a distillation column, changing the contact surface, etc, can change the throughput. Similarly, studying impeller design in the reactor, or in plain English, "stirring the brew properly" can increase reaction rates. "The first thing is to find out what are the factors limiting the reaction rate in a plant," says Prof. J.B. Joshi of the University Department of Chemical Technology (UDCT), Mumbai, one of the busiest industry consultants. Without mentioning names of companies, for confidentiality reasons, Joshi reels out example after example, of benefits from applying scientific methods to debottlenecking. In fact, he derives great intellectual satisfaction from these exercises. As a result of his extensive research into reactor design, using hitech tools like laser dopplerimetry, and vast consulting experience, he teaches a course on multiphase reactor design at UDCT, only one of its kind in world.

"One needs to do just about 40-50 laboratory experiments in a small one- litre capacity reactor to understand the process," Joshi claims. He has developed new methods involving Gamma Ray Tomography to study running plants without disturbing them. The results have been so fantastic that he is one of the most sought after consultants by even international giants like ICI. For example, his work has improved the process developed by the Indian Institute of Petroleum, Dehradun, for cracking heavy petroleum residue in a refinery (vis breaking) to get more diesel and kerosene.The non-invasive Gamma Ray Tomography technique is being applied to "vis breaking" at the IOC refinery, near Baroda, which can yield a 10 per cent increase in the middle distillates (diesel, kerosene, naphtha). In plants of millions of tonnes of capacity, this can be a substantial gain. In fact, this is an example of advanced debottlenecking where quality and composition of the products can be changed without any significant addition of equipment. The end is achieved purely through better reactor and process design. Another striking example of this is the way Reliance has understood the PVC process. The result: a PVC plant designed to produce 180,000 tpa is today producing nearly 300,000 tpa, thereby amazing even the licensors - Geon. Reliance consistently beats financial analysts’ projections by seating it plants, turning into reality Sharma's catch phrase, "more from less".

Joshi points out such work can give " better quality products with lower impurity profile, higher selectivity and lesser load on the environment Contrary to common perception, both Joshi and Sharma emphasise the fact that debottlenecking is not just for large commodity chemical companies but will yield even higher returns for specialty chemical companies. Joshi cites the case of a company which was making a specialty chemical with a market price of about Rs200 a kg. The detailed analysis of the process led to a 20 per cent increase in the yield almost increasing the profit margin by Rs40 a kg. This is a win-win exercise. Not only does the company benefit through better margins but the quantum of effluents, as in the case of dyes and pharma companies, can also be greatly reduced through better conversion. "In many cases a 100 per cent material balance can be established," claims Joshi. Practically nothing will be wasted. This is what Sharma calls "converting liabilities into assets".

Rajeev Pandia, managing director, Herdillia Chemicals, who applied some of Sharma's recipes, concurs: "Some of the waste products which we were burning were converted into fumaric acid, and there were even times when the price of fumaric acid in the market was higher than that of the primary product, pthalic anhydride," he adds.

The next level of debottlenecking is termed knowledge engineering by Sharma. This might involve development of new and better catalysts with higher selectivity, etc. At times the developments have already occurred elsewhere in the world and one needs to understand them and change the catalysts.

"All these steps require a certain willingness on the part of the management to take risks," says Joshi and this he claims to have found in plenty in mid-sized companies with Rs100-500 crore turnover. The returns to companies too have been handsome.

"There are other side benefits of this debottlenecking exercise", claims Pandia. "The multidisciplinary engineering team from technical services, R&D, operations, etc, which gets involved, gets so charged by this process, that it has very good HRD benefits," he adds. A senior Grasim executive confirms this. He claims that debottlenecking is a highly creative process and he greatly enjoyed it when he was a plant R&D engineer.

When the exports are under severe pressure and there is heavy competition from crisis-hit Asian countries, one way to ensure you don't lose your markets is to supply products of premium quality consistently. Debottlenecking helps in achieving this, claims Joshi, and cites the success in exports of Arti Organics, Alkyl Amines, Herdillia Chemicals and so on.

Observers of East Asia claim that many companies there are becoming leaner and meaner during the present crisis and might come out with even more vigour internationally at the end of the crisis. Complacent Indian companies who take shelter in the fact that the crisis in India is not so severe might thus be jolted out of their wits in a couple of years. However, the industrial downturn has definitely made some Indian companies smarter and more productive. Realising its importance, the Indian Chemical Manufacturers Association is planning a workshop on debottlenecking for the benefit of its members. The unpronounceable word is obviously yielding pronounced results.

Wednesday, October 10, 2007

UDCT, Indian Chemical industry

Business India, March 14-27, 1994

Catalyst without compare
The University Department of Chemical Technology (UDCT), Bombay, is justifiably described as the brain behind the Indian chemical industry
Shivanand Kanavi



Wandering the corridors, the labora­tories and library at the University Department of Chemical Technology one encounters some unusual sights for an academic institution. You might find Dr Gharda of Gharda Chemicals poring over the latest chemical abstracts in the library, or Rajeev Pandia, managing director, Herdillia Chemcials, lecturing in a classroom or, some other industrialist conferring with UDCT director, Prof M.M. Sharma, fishing for ideas for new projects. All testimony, if any were needed, to the fact that UDCT truly qualifies to be called the brain of the Indian chem­ical industry.

The UDCT, housed in an innocuous grey sand­stone building in Matunga, a suburb of Bombay famous for its Udipi restaurants, is a truly world class centre of excellence in chemi­cal engineering. It has provided technical man­power to industry, spawned entrepreneurs, provided highly valued industrial consultancy" while at the same time actively participating in the formulation of government policy on the chemical industry. Besides, it does world-class research.

If this sounds like an exaggeration, then a visit to UDCT and a session with Prof Sharma would dispel that impres­sion. Prof Sharma, a product of UDCT and Cambridge, an international author­ity in chemical engineering and the first Indian engineer to be made a fellow of the Royal Society of the UK, typifies the UDCT spirit. Having been on umpteen corporate boards, he speaks eloquently about the problems and prospects of the Indian chemical industry. With equal felicity he speaks of global trends; after his stint at Du Pont, US, as a consultant for a year, the company was so dazzled, That they admitted to another well-known Indian chemical engineer that they needed several specialists to comprehend all that Prof Sharma talks about.

Prof Sharma pioneered the study of multi phase chemical reactions, that is solid-liquid, liquid-gas, solid-liquid-gas and so on, leading to scientific reactor design. The two volumes on the subject he co-authored have become standard ref­erences internationally. His work on microphases is one of the few genuine Indian contributions to chemical engi­neering. He has been on a number of com­mittees to advise the government on policy matters for the last 30 years.

Set up in the thirties to assist the textile industry, UDCT became a unique centre for the study of chemical engineering at a time when the field was not even taught in Europe. Today, besides imparting world class training in chemical engineering, UDCT has very active departments in food and fermentation technology, dyestuffs and intermediates, paints, plas­tics and polymers, textile chemistry and fibres, oils and fats, flavours and per­fumery, pharmaceutical technology and pharmacy, besides science departments.

Its graduates, post-graduates and PhDs occupy key positions in the Indian chemical industry and a large number are to be found in international chemical giants like Dow, Du Pont, Shell, Mon­santo, Merck, Amoco, etc. Due to its pio­neering nature and reputation as a centre of excellence, UDCT has had consider­able autonomy of operation. But being formally tied to Bombay University slows down the pace of curriculum change, which is essential if it must keep up with industry's rapidly evolving requirements. Now moves are afoot in the University to make the department for­mally autonomous, which would quicken the pace of change.

The most exciting frontline work being done at the department of chemical engineering is in Prof J.B. Joshi’s laboratory. He has been studying what goes on inside a chemi­cal reactor using lasers. For a chemical reaction to take place fast enough and give good yields the critical fac­tors are the concentra­tion of reactants, pressure, temperature and the catalyst. How­ever, what is important for a chemical engineer involved in reactor design is the way the reactants come in contact with each other or, in lay terms, the way they are mixed. Normally in a liquid-liquid or solid-liquid reaction, mechanical mixers called agita­tors or impellers are used. In liquid-gas and liquid-liquid reactions one can also be sprayed into another. Another tech­nique used in gas-liquid and gas-liquid-­solid reactions is 'sparging' or bubbling the gas.

The mixing is limited by factors like actual surface area of contact between reactants, which needs to be increased while suspension of the catalyst has to be critically controlled. Too little suspension of the catalyst may slow down the reac­tion while too much agitation can lead to loss of expensive catalysts. One also needs to have more or less homogenous mixing to avoid hydrodynamic stresses. This requires precise knowledge of turbulence caused by any particular type of mixing. Normally a large part of impeller design is done by conventional wisdom developed through trial and error.

Prof. Joshi, how­ever, constructs scaled down glass reactors of 25 to 100 litre capacity in his lab. When the mixing is going on he shoots a laser beam that is split optically to produce two coherent sources. They are then focused at a point within the reactor. The normal pattern of interference fringes formed by the beams is disturbed due to motion of the fluid at the point. If the interference pattern and the scattered light is studied then there will be frequency shifts in the scattered light depending on the velocity of the fluid at the point due to the well-known Doppler effect. This technique is called Laser Doppler Anemometry.

By knowing the distribution of turbu­lence all over the reactor and studying it as a function of impeller design, he comes up with the appropriate design for any particular process. The study of turbu­lence using lasers has led to a rich exper­tise in Joshi's team and newly designed reactors have been installed in Bombay Oil Industries, Chemo Pharma Labs, Indian Organic Chemicals, Hico Prod­ucts, Jaysynth Oil Mills, etc, and the tech­nology has been transferred to Reliance Heal Transfer for manufacture. This expertise along with the computer soft­ware developed is unique and sought after internationally. Soon he has plans to develop a total package for reactor impeller design.

His team has also developed a number of extremely useful technologies that reduce pollution drastically and produce valuable products from distillery waste, cyanide waste, nitrogen oxide wastes, etc. His work fetched him the prestigious S.S. Bhatnagar award for engineering sci­ences in 1992.

While many drug manufacturers have been worried about the effect of the prod­uct patent regime in the post-Dunkel era, Prof V.M. Kulkarni in the pharmaceutical technology division is unfazed. Operat­ing under a soft patent regime, the Indian drug industry has not invested in the dis­covery of new drug molecules. Thus he did not find many takers for his passion for drug designing. But now things have changed and money is pouring in. Dr Reddy's Laboratories have given him sophisticated computers and expensive software worth nearly Rs.30 lakh to design new drugs. He is extremely confi­dent about the prospects of India becom­ing a major player in drug designing due to the availability of highly skilled and inexpensive manpower. There are many such technology stories in UDCT's rather modest labs.

Prof. Sharma has no time for controver­sies over basic vs. applied science. His method of work seems to be to take up problems relevant to industry, look at the more basic aspects of the problem, solve them at a high theoretical level, generate ideas, check them out on a laboratory scale and then advise the industry. There is a culture in UDCT of faculty members doing academic work of a very high stan­dard while solving problems relevant to the industry.

For example, Prof J.B. Joshi has been doing internationally acclaimed research work even while earning the highest con­sultancy fees in Bombay University. When asked about the rationale of a ceil­ing of Rs.4.5 lakh on consultancy fees imposed by the University when a third of it goes to the cash-starved University, Joshi says, "It is prudent to have some sort of ceiling because after all my first commitment as a teacher is to my students Also, rightly, we cannot use university facilities like labs, etc, for consul­tancy work. After all if my sole aim was making money, then I would not have joined academia!”

Unlike most other insti­tutions UDCT seems to suffer from a problem of plenty in consultancy.
While IITs are now walking up to the idea of con­sultancy and industrial research. consultancy has been a professional norm for the UDCT faculty for nearly 40 year, A large number of companies like Herdillia, Tata Chemicals, Bombay Oil, Indian Organics, Gharda Chemicals, Hindustan Lever, Amar Dye Chem, Indian Dyestuffs Industries, Asian Paints, Nocil, PIL, Reliance Heat Transfer, Industrial Per­fumes, Dharamsi Morarji, Tata Pharma, Lakme, National Rayon Corp, RCF, Alkyl Amines, Western Pacques, Poly­chem, Dr Reddy's Research Foundation, CIPLA, Lupin - a virtual who's-who of the chemical industry - besides scores of small scale industries, have had the benefit of the expertise available at UDCT.

With this kind of utilitarian culture it is not surprising that many of UDCT"s alumni and even ex-faculty members arc successful businessmen. Dr Keki Gharda of Gharda Chemicals, Dr Anji Reddy of Dr Reddy's Labs, Mukesh Ambani of Reliance, I.A. Modi of Cadilla, the three Parekh brothers of Pidilite, R.M.Kedia of Kedia Chemicals, Dr K.V. Mariwala of Bombay Oil Industries, Nikhil Meswani of Reliance Petro, Dr Atma Gupta of Armour Polymers, V.G. Rajadhyaksha of Hindustan Lever, and J.M. Nadkarni of Bombay Paints are just a few names that come to mind. The full list is extremely impressive and also includes a large num­ber of small scale industrialists. The alumni have also been generous towards their alma mater in cash, chemical sup­plies, scholarships and endowments. No wonder, UDCT's diamond jubilee this year will be proudly celebrated by the Indian chemical industry.

Tuesday, October 9, 2007

Indian S&T 1947-97

Business India, August 11-24, 1997

Prisoner of autarky

Indian S&T is yet to recover from the fallout of autarkic policies and the Pokharan nuclear explosion

Shivanand Kanavi

Along with the rise of the modern nationalist movement and an attendant intellectual renaissance, the first quarter of the 20th century saw the rise of a few brilliant scientists like S. Ramanujan, C.V. Raman, S.N. Bose and M.N. Saha. They won worldwide acclaim for their work in number theory, molecular physics, quantum statistics and astrophysics. Although Europe was the seat of high science at that time, they did not emigrate and instead continued their pursuit of science in India despite the paucity of funds and poor educational and research infrastructure. In the process they also trained a few young researchers. The research groups pre-Independence were centred around these individuals in the mould of guru shishya parampara.

Institutional science
Then came Independence and along with Nehru and his brand of modernisation, a new breed of scientists like Homi Bhabha, Vikram Sarabhai and Shanti Swarup Bhatnagar took over as science administrators. Having studied in Europe, Bhabha and Sarabhai saw the rise of organised science in the period between the two World Wars, and they tried to repeat the experience in India by building government-funded R&D institutes outside the university system. The era of institutional science began.

Their access to Nehru and prominent industrial houses helped Bhabha and Sarabhai in raising new institutions like the Tata Institute of Fundamental Research (TIFR) and the Atomic Energy Establishment (now called the Bhabha Atomic Research Centre) at Mumbai and Physical Research laboratory (PRL), at Ahmedabad ..

Bhabha attracted a large number of talented scientists and engineers from India and abroad to work at the institutes. He understood that Indian science would gain only through international contact. He not only sent a large number of young scientists abroad for higher studies but also ensured that a large number of distinguished scientists including Nobel Laureates visited TIFR to give lectures. He modeled TIFR after the Institute of Advanced Study at Princeton and encouraged the development of first rate groups in mathematics and physics. Expertise in many emerging fields like nuclear physics, electronics, computers, radio astronomy, and elementary particle physics was developed here.

Under Sarabhai's leadership the PRL at Ahmedabad, with its emphasis on cosmic rays and radio physics, became the birth place for Indian expertise in space sciences. Besides being excellent basic research centres, TIFR and PRL were the cradles for the nuclear, and space programmes that took off later.

Shanti Swarup Bhatnagar wanted to develop the more mundane industrial technologies. A council to encourage industrial research had been set up by the colonial government in 1942. The idea was developed by Bhatnagar with Nehru's active encouragement and a network of laboratories starting with the National Physical Laboratory, (Delhi) and the National Chemical Laboratory (NCL, Pune) were built in 1950. From this grew the Council of Scientific and Industrial Research (CSIR) which at present is the largest chain of publicly funded research laboratories in the world comprising over 40 laboratories.

Within a decade of the formation of the Atomic Energy Commission in 1948, India became the first Asian country to build its own research reactor-Apsara in 1957 at Trombay. The problem that worried Bhabha was how to use India's limited resources of uranium to produce electricity without enriching uranium and more importantly how to use the vast reserves of thorium on the beaches of Kerala. The Canadians came forward with an answer with their Pressurised Heavy Water Reactor technology. India adopted this, while at the same time buying conventional reactors from General Electric Company of USA to gain experience in nuclear power. As a result, Tarapur Atomic Power Station was built on conventional grounds and a contract was signed with the Canadians to build the Rajasthan Atomic Power Station.

While the Trombay group went ahead in acquiring expertise in nuclear physics, the PRL Group under Sarabhai started the space programme, modestly. Sarabhai negotiated with the Bishop of an old church at Thumba (near Thiruvananthapuram) to use the premises to fabricate the first sounding rockets in 1963. Since everything in the field of rocketry had to be learnt from scratch, Sarabhai used his contacts in NASA, and among the scientists involved in the French and Russian space programmes to get as much information as possible. After Bhabha's death in an Air-India crash near Geneva in 1966, Sarabhai took over the leadership of both space and nuclear programmes. However, matters changed drastically for the nuclear programmes after Sarabhai's death in 1972. To the then prime minister, Indira Gandhi, atoms were an instrument of power. Within a short while, she reoriented the programme towards generating a bomb.

Pokharan fallout
The underground nuclear explosion at Pokharan in the Thar desert in 1974 changed the course not only of the nuclear programme but of Indian science in general. Till-today, Indian R&D institutions and technology programmes cannot import a state-of-the-art CNC lathe or a special purpose pump much less hi-tech electronics and supercomputers, thanks to the embargoes. In fact, Canada abandoned the Rajasthan nuclear power project mid-way.

The wisdom that flowed from the PMO at this time was self reliance and import substitution. Nobody asked the question 'Is it cost-effective, original or globally competitive?’ as long as the science mandarins claimed it was a breakthrough in indigenous import substitution. The darkage of post-Independent S&T began. From which we have yet to recover.

With great difficulty; nuclear engineers have today managed to grasp the Pressurised Heavy Water Reactor technology, but in the process, are left with obsolete technology. A latecomer like South Korea with S&T infrastructure hardly comparable to India's, today produces 10,316 MW of nuclear power with 11 nuclear reactors, while India has an installed capacity of only 1,700 MW from 10 nuclear reactors.

Moreover, the transparency of the nuclear programme during. Bhabha and Sarabhai's time, later turned into extreme intolerance towards critics. Today there are serious questions to be raised about the money spent on atomic energy and the returns on it.

However Satish Dhawan, who took over the leadership of space programme in 1972, retained the openness and informality required for the cutting edge in science and engineering. Even though the technology embargoes were forcing Indian Space Research Organisation too to reinvent the wheel, he used the build-or-buy choice intelligently. Solid fuelled rocket technology had obvious applications in missiles and hence- no one was ready to give it. So Dhawan concentrated on developing it at Thiruvananthapuram.

Liquid fuelled rocket engines, which are the more efficient and necessary components of satellite launching technology, were a different cup of tea. Using his excellent personal contacts, Dhawan convinced the French to transfer the liquid fuelled rocket technology. He also formulated a well charted road map to reach the goal of satellite launching capability. Another group concentrated on learning the intricacies of remote sensing and communication satellites. When they did not get an electronic component from the US they either built it themselves or bought it -from the Europeans or Japanese. Dhawan also negotiated for free launches from the French and the Russians. Today the space programme stands out as one of the few publicly funded initiatives in India that has achieved world class standards.

With the gradual opening up and liberalisation in trade in the 1980s, a new initiative to focus on certain technologies was taken by the then PM, Rajiv Gandhi. Operating "on a mission mode", where a multidisciplinary group comes together to achieve a target and is then disbanded without creating bureaucracies, became the new paradigm. Sam Pitroda and his team in the telecom technology mission came to the fore. Belatedly India decided to enter the era of digital telecommunications. The result was the switch designed by the Centre for Development Of Telematics (C-DOT) meant for small exchanges. However before C-DOT could deliver the large switch it suffered a setback. In an increasingly fractured and revengeful polity Pitroda's closeness to Rajiv Gandhi was the excuse used by the succeeding government to cripple the telecom mission. So in the 1990s, when worldwide, telecom is undergoing fast technological changes, India once again lags miserably.

In the last ten years, successive governments have been busy fighting for survival and the initiative for the development of S&T has fallen to an extent on lower level R&D managers. Many science administrators have
created bureaucratic fiefdoms while a few have used the opportunity to reform.

For example R.A.Mashelkar, director of NCL, used the opportunity to make his colleagues aware of their intellectual property rights and pushed them towards proactive global technology marketing. NCL today has emerged as a world class centre in catalysis and polymer science. As the director general of CSIR, Mashelkar now has the task of converting his slogan of 'research as business' into reality.

At cross roads
Research in the private sector has been a joke so far. Equipment and wages of personnel involved in routine quality control, which is part of the manufacturing activity, listed by the industry as R&D expenditure to avail of the tax breaks. However the new GATT regime and the pressure on India to change, its patent laws is forcing a handful of domestic pharmaceutical companies to invest in new drug research.

If the state of bio-technology is poor due to the indolence of the private sector the fate of the other major technology of the 21st century-infotech- has been sealed by a luddite attitude towards computers. As a result there is hardly a domestic base for information technology without which no real software industry can come into being. The software industry requires the installation of a large number of computers in the government, financial sector and the corporate sector who then drive the market for application packages. However due to flawed policies that looked at computers not as an opportunity to increase productivity and create new jobs but as villains that would take away jobs India today has a pitifully small number of computers, hardly a quarter of those installed in China, leave alone other advanced countries. In the circumstances, Indians have developed core competency in customized solutions and software services for corporate clients abroad. This sector is growing at an impressive 50 percent growth rate. Software product development with higher margins and visibility has started only in the 1990s, that too on a low key. As an observer said: "What software industry do we have, we have not produced even a video game.”

To sum up, in the last 50 years Indian S&T has gone through a series of periods characterised by brilliant scientists before Independence, institutional science in the 1950s and 1960s, autarky and bureaucratisation in the 1970s and 1980s and opening up and the chance to leverage ourselves in knowledge based industries in the1990s.

Will our government, science satraps and entrepreneurs seize the hour or will we keep marking time, hearing inanities about the “third biggest pool of scientific power”?

M M Sharma, Indian Chemical industry, UDCT

Business India, February 10-23, 1997

The chemistry of industry
Prof M.M. Sharma, FRS, was the first Indian engineer to be made Fellow of Royal Society of London. Recently he was awarded the Leverhulme Medal established on the occasion of the tercentenary of the Royal Society “in recognition of his work on the dynamics of mu1ti-phase chemical reactions in industrial processes”. The medal has been awarded to only five other chemists and engineers since 1960.

He has made significant contributions in making the University Department of Chemical Technology (UDCT), Mumbai, of which he is the director, into a world class centre of excellence in chemical engineering. He spoke to
Shivanand Kanavi on industry-academia interaction.


How did you acquire the mindset of doing basic research of very high value and at the same time being concerned about commer­cialisation of scientific results?
The answer to your question on my interest in interaction with indus­try goes back to the roots of the organisation (UDCT). There is no family history of business or great academic work. The desire to link practical problems with academic work is a later development.

Early faculty members at UDCT, like Professors Venkatra­man, G.P. Kane, G.M. Nabar, N.R. Kamath thought that UDCT should have organic links with industry in a professional way and not in terms of lip service.

As soon as India became inde­pendent, there was a vacuum. Who will advise textile mills in textile processing? The industry knew only spinning and weaving. After the Second World War, BIOS reports became available, to pro­vide the guidelines for organic chemical industry. Thus, a mutually beneficial relationship could be sustained.

From my Cambridge days, I had been publishing papers in Faraday Society Transactions, etc, but I was working on a problem which had links with industry even in the puritan atmosphere of Cam­bridge. In fact, those days, I was lucky to have an idea patented in my name and sell it to Shell International. My original con­viction became terribly strengthened with this exercise.
I would say that the monograph that I wrote with my mentor, the late Professor P.Y. Dankwerts, FRS, GC, in Cambridge, on 'Absorption of carbon dioxide in amines and alkalies', gave me great satis­faction. I think it became a sort of classic in chemical engineering where we explained how from the very first principles you go to the design of final industrial equipment.

What led to your celebrated work on 'microphases'?
At UDCT from the beginning, we had taken up problems, which were very heavily idea-centred because we had no budget. A problem of making precipi­tated calcium carbonate (which goes into toothpaste, etc), came to us. On the face of it, it was very simple. Calcium oxide plus water gives calcium hydrox­ide, which, with carbon dioxide, gives calcium carbonate.

At that time an idea came to us about the role of 'microphases', a phrase that we used much later. Microphase is a phase where the characteristic dimension is less than the diffusion path. In simple language, particles, which are sub-micron to few microns in size - it could be a small bubble, a small liquid droplet, solid particle - constitute the microphase. The microphase changes the dynamics of the process. For example, when you hydrate calcium oxide you get particles within micron range with­out expenditure of energy. Therefore, you see how real life problems are the harbingers of problems of great the­oretical interest!
It is a great pleasure for an applied scientist, when his idea works, and he can demonstrate its academic purity by way of research publication. It gives you a kind of thrill, which has a powerful catalytic action.

You mentioned the BIOS reports. Can you explain what they were and how the war triggered applied research in UDCT?
After the German defeat in World War II, teams were formed with experts from allied forces to visit every German chemical plant and other plants and find out all the details about their manufacturing processes. German dyestuff industry and textile aux­illiaries were well known. The mother company was IG Farben from which Bayer. Hoechst and BASF were later born. The British Intelligence Office pro­duced these reports. Every detail of the manufacturing process was given in these reports.

They were then the starting point for entrepreneurs in India to start industries, we at UDCT had access to these reports and they were a fantastic source of infor­mation. The entire recipe was given in detail. Indians had to learn textile pro­cessing. Our textile-processing course was immensely helpful. It provided trained manpower when British experts had left.

Textile and sugar are mother indus­tries in India. They gave impetus to many things. All the original chemical compa­nies in India were textile houses ­Mafatlals, Sarabhais, Srirams in DCM, Jaikrishna Harivallabhdas. Ambika Mills, Atul. etc. From textiles to dyes and bulk chemicals is how we developed in India. Plastics and synthetic fibres, which dominate the chemical industry today came into the scene much later, in the late 1960s and 1970s.

Your advice is sought by almost the entire Indian chemical industry, Why not develop technology and licence it rather than be a consultant?Licencing is a complicated business. To advise industry on how to get more from existing assets is the most rewarding experience in terms of relationship between an academic and industry. Industry gets benefit immediately: more profits, less load on effluents, much more throughput out of existing equipment. The academic gets the benefit of seeing his ideas work and gets emboldened. It also buttresses his income. The student gets tremendous advantage because the quality of lectures he gets improves.

There is lot of talk in India about uni­versity-industry interaction, but it is only talk. People never put it into practice.

Consultancy by faculty members should have a wider base. If one person is involved in a faculty of 20, the spread fac­tor is very limited. At least one-third of the faculty should be involved.

Last year we generated Rs.43lakh through consultancy. Bombay University got one-third of it. This year will we be able to do it? Was it a freak year? No. by all indications we will make it this year also.

Lawyers, chartered accountants, doc­tors etc. practice consultancy, why not engi­neers? Of course, a high level of professional integrity is required. One black sheep can give a bad name to the institute. Any underhand dealing will get exposed - sooner rather than later.
Intellectual curiosity is also satisfied along with material needs and we have a greater chance of retaining a good per­son. This is important; after all an acade­mic's salary is nowhere near corporate salaries.

What do you think about sending teachers to industry on a sabbatical? Or about academics being on the boards of companies?
We have practiced these things very rig­orously. In the beginning, instead of sending a faculty member for a whole year, we see them on vacation place­ment so that he does not have to take leave and worry about continuity in service etc. A number of people have been on the board of companies and even many companies simultaneously. We encouraged it.
We have created as number of visiting professorship through private endowment, for persons from industry. We have not left any stone unturned.
Industry is realizing that their engineers need to upgrade and retrain. So they are requesting us to design refresher courses of 2-3 weeks’ duration.
Being science-based, the chemical industry is receptive to new ideas. If -you see Department of Science and Tech­nology's booklet on R&D in Indian indus­try, it is the chemical industry which leads; largely domestic companies and especially the technocrat-driven companies. 'The big C in their capital is technology and they have to be superior to be competitive nationally and internationally.
Of course, in India there is horizontal pilferage of technology because of Which the industry has acutely suffered in the last 20 years. The cost of innovation is high while that of pilferage is zero.

What is your view on the IPR controversy?Let us be very objective. When the cost of development is abnormally high and that too based on private money, it will be I treated as property. After a drug or agro­chemical molecule has been found, anybody can improve the technology and sell at a lower cost because the developmental costs have been borne by someone else. Why are we feeling diffident that we can­not generate ideas of that calibre?

I will give an example of missed oppor­tunities from chemistry. N.R. Iyengar had a brilliant idea to make an intermediate for rubber chemicals. He published that paper in Tetrahedron Letters. If he had the awareness, he would have patented it. Two or three years later there was a patent from Monsanto where the first paper referred to was N.R. Iyengar's! Based on that idea a commercial plant can be put up which costs less and is less polluting. A known product but made by a better route. I am just giving an example. If he had patented it, it is quite likely that Monsanto would have bid for it. He could also have then published it.

The debate on what can be patented and what cannot be, goes on all the time. An obvious thing cannot be patented but there is too much sensationalism in India ­"neem is being patented, tulsi is being patented.” etc. Something, which we know in everyday life, cannot be patented.

With the increasing integration of the Indian economy with the world econ­omy, there is a fear that Indian R&D will suffer. What is your view?I am convinced that globalisation will give a big boost to indigenous R&D and that it will get recognition internationally. The cost of research is so much lower in India than anywhere else. Talent is in reasonable abundance. All said and done I here is a worldwide trend against sharing technology. Therefore, the desire to come out with alternate technology, which is superior and patentable, will get a boost. Even in this liberalised atmosphere, many are not able to put up plants because nobody is ready to sell the technology to them. This will continue, because the developed nations perceive India as a potential competitor

Thursday, October 4, 2007

Genetic Engineering, Bt Cotton

Business India, December 14-27, 1998

To terminate or not to…………

Violent agitators want the farm experiments on genetically engineered cotton to be terminated. Business India examines the issues involved

Shivanand Kanavi

Professor Nanjundaswamy and his followers in the Karnataka Rajya Raita Sangha (State Farmers’ Association) are very angry; in recent weeks they have been uprooting and burning boll worm resistant cotton plants, from experimental farms in Bellary and Raichur in Karnataka. Others have engaged in similar vandalism in Andhra Pradesh. Taken by surprise, farmers who had volunteered for the experiments have opposed these attacks and asked for police protection. The agitators allege "Terminator technology is being tried on unsuspecting third world farmers by the multinational seed company Monsanto." Some ministers in Andhra Pradesh too have fallen prey to agitators' propaganda and asked for banning of the experiments. Dr P.K. Ghosh, advisor to the Department of Biotechnology, has however deplored these attacks, clarifying that the experiments have nothing to do with the terminator gene and are about boll worm resistant cotton. Moreover, they are being conducted under the strict supervision of various agencies of the Central government. But no one is listening.

Comparison between Luddites and the crusaders against experiments in genetically engineered cotton ends with their violent methods. Luddites were manual textile workers displaced by the advent of machinery in early 19th century England, who went about expressing anger against their misery by smashing up machinery. They saw machines as the cause of their condition. The current agitators claim to be farmer's representatives and well-wishers but are preventing farmers from being voluntary participants in experiments whose successful outcome would lead to a better cotton crop, with lesser use of insecticides.

It is patent disinformation to say that current experiments are to do with the "terminator gene.” The experiments are to do with cotton that is genetically engineered to resist boll worm attack. It has been known for almost a century that a particular type of soil bacteria produces proteins that are toxic to some common pests attacking cotton, corn and potato. A German scientist, Ernst Berliner, who rediscovered it in 1915, in Thuringen, named the microorganism, Bacillus thuringiensis (Bt). Since then this bacterial culture has been used as a commercial insecticide.

Monsanto's biotechnologists patented in March 1996 (US patent No: 5,500,365) an ingenious way to take out the genes from Bt, that are responsible for the production of toxic protein that has insecticidal properties. They then implanted these genes into cotton seeds. Such genetically engineered cotton seeds produce the toxin that will kill boll worms - a major pest that attacks the cotton boll. If a boll worm larvae eats a leaf or any part of the cotton plant, then the toxin attacks its gut, leading to its death much .before it can harm the crop. Monsanto sells this technology under the trademark Bollgard.

Several seed companies have been licensed the Bollgard technology in the US. After completing all the regulatory trials, checking for toxic effects on human beings, birds which eat the insects etc, the technology has been commercialised. Over 2.2 milllon acres of cotton growing area, that is 22 per cent of the cotton growing area in US, was planted with Bollgard cotton seed in 1997. It was found that 60 per cent of Bollgard cotton was not attacked by boll worms at all, and others applied anti-boll worm insecticide only once as compared to four to six applications in conventional cotton. It is also being planted in Australia and China.

India is the world's largest producer of cotton (32 per cent in 1995-96). However, due to the threat of boll worm, cotton requires one of the most intensive insecticide application. It is estimated that agrochemicals worth Rs.1,590 crore were used by Indian cotton farmers in 1995-96 alone. Thus, one would assume that Bollgard technology, if proven in Indian conditions, would be a boon to cotton growers and the environment alike.

Terminator gene
Terminator gene the villain in the agitator’s plot is the name given to a concept patent obtained by Delta & Pine Land and the US Department of Agriculture by its opponents. It has nothing to do with the experiments being conducted under strict government supervision.

In March 1998, Delta & Pine Land, the largest cotton seed seller in the US, was granted a concept patent along with the US Department of Agriculture (US Patent No: 5,723, 765, control of plant gene expression, Inventors: M.J. Oliver, J.E. Quisenberry, N.L.G. Trolinder and D.L. Keim). The concept, when further developed and implemented, can lead to seeds that will yield normal crops, though the second generation seeds will be rendered sterile. If successful this technology can stop the farmer from saving high yielding seed incorporation this technology, for the next sowing. They will be all sterlile, this will force him to go back to the seed company. This has been termed “terminator gene” technology by Pat Mooney of Canada-based Raral Advancement Foundation International, and organisation that campaigns against seed companies like Monsanto (see http://www. rafi.ca).

The technology is highly complex and requires all such seeds to be soaked in the antibiotic tetracycline before sale. The cost of technology and tetracycline are going to make such seeds extremely expensive. Thus, if any farmer were to buy them it can only be for extraordinary yields and other benefits. Moreover, ad for as hybrids go, the farmers is used to buying seeds every year since the hybrid vigour diminishes by almost 50per cent in the second generation seeds. Thus the commercial necessity and viability of this technology is under question.

Biologists like Martha Crouch of Indian University, and several NGOs have expressed the fear that such seeds, if ever produced, can render other plants of the same species grown nearby also sterile through what is called outcrossing, they also warn against possible toxic effects on insects and birds. Naturally, the terminator seeds have to be thoroughly tested before approval. Moreover , even if the regulatory authorities US approve such seeds, other countries need not follow suit. Even under WTO agreements on Intellectual Property Rights and other related agreements regarding plant varieties, individual countries can disallow certain varieties as inimical to public good, good security, environmental concerns etc. under a sui generis system.

Terminator technology is only confined to Delta & Pine Land’s labs and no seed using this concept has yet been produced for rigorous regulatory trials , leave alone commercial production. The technology has remained and important scientific feat in terms of genetic engineering, but of no real world consequences yet. A parallel can be drawn in the closing of sheep Dolly, by scientists in Scotland last year. A great achievement in life science. But if one were to start a campaign against it on ethical grounds saying this can lead to human cloning, Nazi eugenics and so on, then it would be highly premature and sensationalist. That is what the preset agitation against Bollgard experiments, is all about!

Monsanto, which has been on an acquiring spree, has made a friendly bid to buy out the controlling share in Delta & Pine Land, the world’s largest cottonseed company. At present, it owns only 7 per cent of the stock, the takeover is expected to be sooth according to Monsanto sources. To claim however, as the agitators do, that Monsanto will acquire terminator gene technology in future and use it in conjunction with its highly successful bioengineered seeds and hence any experiments using Monsanto’s present technology, even if they are beneficial to the Indian farmer, should be terminated, is highly convoluted, to say the least.


Biotech revolution
Mahyco, the leading cotton seed company in India, hence tied up with Monsanto in a joint venture, Mahyco Monsanto Biotech India Pvt. Ltd. to implement Bollgard technology in its own best -selling varieties. After all, Bollgard seeds of any other country cannot be used in India. So Mahyco has done considerable research leading to absorption of Bollgard in 10 of its varieties. It is these varieties that are being field-tested in 40 centres all over India under different agro-climatic conditions. Many of them are Mahyco's own research farms. However, some of them belong to private cotton growers. The tests are being conducted under the strict supervision of the Department of Biotechnology of the Central government. Due to the sensitive nature of biotechnology, over half a dozen committees working under the biotechnology and environmental departments are reviewing the results. When the trials were almost complete came these sudden attacks, causing dismay among scientists.

Mark Wells, national marketing manager of Monsanto in India says: "Genetically engineered crops are being scrutinised and tried under the strictest of conditions like any drug meant for human use. And rightly so. We find that highly competent Indian scientists are monitoring the tests. Monsanto will not provide any technology that will adversely impact the environment, current agricultural practices or force farmers to use our technology. New products and technology and must increase farmers’ income otherwise they will be rejected by them.”

Indian agricultural scientists have had more than three decades of experience in breeding hybrids and high yielding varieties. In fact, much of the enthusiasm for cotton in the past 20 years among farmers is due to the introduction of new high yielding varieties by the Indian Council of Agricultural Research (ICAR) and the Agricultural Universities. It is however strange that the network of agricultural universities, with vast experience in in situ experiments, are not involved in the current trials. Vijay Kumar Gidnavar, deputy director of research, University of Agricultural Sciences, Dharwad says; “we are looking forward to the results of the experiments. Bollagard is a major achievement in plant biotechnology and its success will give a fillip to biotech work among Indian scientists as well. In fact, we do have several biotech projects going on at the laboratory level already”

Let us not miss it
Biotechnology can yield a number of benefits for farmers. In fact, the report of the World Bank panel on transgenic crops, authored by eight internationally renowned scientists, including M.S.Swaminathan, states: “Transgenic crops are not in principle more injurious to the environment than traditionally bred crops. Transgenic crops that are developed and used widely can be very helpful, and may prove essential, to world food production and agricultural sustainability. Biotechnology can certainly be an ally to those developing integrated pest management and crop management systems.”

For example, potato impregnated with another gene from Bt has proven resistant to the potato beetle. Similarly, protection from corn borer for maize has been provided by another gene from Bt Besides insect protection, biotech can lead to better weed management, thereby increasing the yields. A major development has been the production of genetically engineered soybean, maize and rape seed that are resistant to herbicides. A broad spectrum herbicide like glyphosate kills most of the weeds and the crop as well, since it inhibits ESPSP synthase, an enzyme essential to plant growth. But biotechnology has enabled scientists to develop seeds thereby making weed control a simple matter of spraying glyphosate. Research is on to develop genetically engineered varieties that are resistant to various fungi and viruses as well.

In fact, mimicking the famous Moore’s law (Gordon Moore, founder of Intel) in micro electronics which states that “computing power of silicon chips will double every 18-24 months”, Monsanto has coined its own ‘Monsanto Law’, which states, “the ability to identify and use genetic information will double every 12-24 months.”

Should Indian agriculture miss this biotech revolution. When it is clear that environmentally friendly intensive agriculture is the only solution to the problem of feeding a billion Indians? One can understand the Frankenstein syndrome- fear of tampering with nature to produce an uncontrollable monster. But then, is not agriculture itself an artifice?